I have a mix of “when we meet” sort of games, and a few more regularly scheduled games.
Enemy Within
I've been running the updated Enemy Within using Warhammer Fantasy Roleplay 4e for maybe like a year now, in person, roughly once or twice a month. We're kind of through Death on the Reik, but its been so heavily modified who knows where the PCs are going.
I pretty much regret using WFRP 4e - I have all of the books and have had fun with it when playing here and there with some friends at cons, but the system is pretty chunky with lots of keywords that get referenced all over, and enough state that you have to track all the time that it is VERY easy to mess up and forget. I kinda with I had just gone with any random version of BRP.
Chronicle of the Cosmic Wound
This is a dark fantasy game set in one of my long-running settings. We're using a heavily home-brewed version of OpenQuest 3 with some stuff thrown in from Dragonbane, BGB BRP, and my own stuff. This is a twice-a-month open table game, although most of the players have been consistent from day one.
The players recently crashed a boat onto a mysterious island that came out of nowhere and "shouldn't be there," so this session we'll see what they do to get off the island. It's got a folk horror vibe, and you can kind of think of the setting as Berserk-ish or probably more appropriately Clark Ashton Smith's Averoigne but ripping off more 12th century Europe than later.
Gradient Descent
I am also running an open table of Mothership in the Gradient Descent dungeon. We have a bunch of regulars but also new people jump in here and there. This is technically the "off" week from Cosmic Wound. The players thus far have started experiencing some of the weirdness related to the "bends" mechanic and impersonator droids, but I won't spoil stuff for people who haven't played this.
Great Pendragon Campaign
I've been running the GPC using Pendragon 5.2 for a few years now, and we're still solidly within the anarchy. Unfortunately my schedule doesn't line up too well with the days we can play, and a bunch of us are often busy with other things, so we don't play as much as I would like, but its fun whenever we do.
One Shots
I run monthly one-shots, typically with the genre and theme randomly generated and slapped together. Most of these are ran in a loose 2d6 vs. 8 sort of psuedo-feeeform, with the rulings reflecting whatever the world is.
Other stuff
Otherwise I'm signed up for Amagadeth which is a playtest science fantasy campaign ran by Spinachcat that I am looking forward to, and I often drop into friends' games here and there when I have the chance.