The implied setting of ‘vanilla’ Troika! is a real fictional sweet spot for me. It is as much an inter-genre collage as other things often called gonzo - but with a flavor very much its own - a bit Lewis Carroll, a bit Spelljammer, a bit Ghibli, and a healthy dose of 21st century weird fiction. It certainly has a wackiness to it - but there are enough genuinely cool and surprising ideas to make it substantial and wacky 
But I also agree with @dozens about the game’s openness - and love the way the community has really embraced the idea that Troika! can be almost anything - and taken the game’s freewheeling attitude as an invitation to be ridiculously, creatively playful.
I’m currently running through a heavily modded version of Blancmange & Thistle in a playtest for my own ultralight/FKR science-fantasy game/toy box - I love how it unrepentantly indulges in the fun of throwing many absurd, but highly interactive situations at players, while letting whatever unifying logic or lore there may be come out in play.